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The Web and Flow of Information in Pharmaceutical
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activities algorithm allow alternatives analysis applications approach batch bound changes Chem chemical chemical process codes column Comp complex components computational concepts consider constraints continuous cost defined described detailed devices distillation dominant dynamic economic effect energy engineering equations equipment et al example experience Figure Floudas flow flowsheet formulation function given global optimization Grossmann heat implementation important increase industry integration interactions involved lifecycle linear major material mathematical methods molecular nonlinear objective obtained operation parameters particle performance phase plant possible potential presented problem procedure process design process modeling programming properties reaction reactor reduced scale selection separation shown shows simulation solution solve specific stage step strategy structure synthesis techniques temperature unit variables