Casarett and Doull's Toxicology: The Basic Science of Poisons |
Contents
History and Scope of Toxicology | 3 |
Louis A Chiodo Ph D Yvonne P Dragan Ph D | 8 |
Principles of Toxicology | 11 |
Copyright | |
53 other sections not shown
Other editions - View all
Casarett and Doull's Toxicology: The Basic Science of Poisons Louis J. Casarett,John Doull No preview available - 2001 |
Common terms and phrases
absorption acid activity adducts aflatoxin agents alcohol aldehyde aldehyde oxidase alterations amines animals antibody antigen apoptosis aromatic assays bile binding bioassay Biochem biotransformation blood cancer carcinogenesis carcinogenic catalyzed cells cellular Chem chemical chromosome compounds concentration conjugation cytochrome P450 cytokines decreased developmental toxicity disease DNA damage DNA repair dose dose-response drug effects enzymes epoxide ethanol example excretion exposure factors formation function gene genetic glucuronidation glutathione glutathione S-transferase hepatic hepatocytes hormones human immune immunotoxicity increased induced inhibition inhibitors interaction involved levels lipid liver lung macrophages mammalian mechanisms membrane metabolism metabolites mice microsomal molecular molecules mouse mutagenic Mutat Res neoplasms organ oxidase oxidative oxygen P450 enzymes pathway percent Pharmacol plasma platelet potential produce proliferation protein rats reactions reactive receptor repair response result risk assessment rodent role shown in Fig specific studies substrate synthesis target TCDD teratogenic Teratology tion tissue toxicity Toxicol toxicology tumor vitro vivo xenobiotics